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Adrienne Cupples, Ph D, Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Avenue, CT3, Boston, MA 02118, Tel: (617) 638-5176, Fax: (617) 638-6484, Genome-wide association studies (GWAS) have identified thousands of genetic variants that influence a variety of diseases and health-related quantitative traits.

The study included 4,231 participants from three CHARGE cohorts: the Atherosclerosis Risk in Communities Study, the Cardiovascular Health Study, and the Framingham Heart Study.Participants in the CHARGE Targeted Sequencing Study had sufficient DNA for sequencing, self-reported ethnicity as non-Hispanic white, and availability of prior genotyping results.



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